Impact of nodular size on the predictive values of gray-scale, color-Doppler ultrasound, and sonoelastography for assessment of thyroid nodules
| Autor: | Yu-rong Hong, Zhi-yan Luo, Ning-bo Wu, Yulian Wu, Xue-ming Liu |
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| Rok vydání: | 2012 |
| Předmět: |
Adult
Male Thyroid nodules Pathology medicine.medical_specialty animal structures Adolescent genetic structures Sonoelastography General Biochemistry Genetics and Molecular Biology Thyroiditis Diagnosis Differential Young Adult Elasticity Imaging Techniques Predictive Value of Tests Humans Medicine Prospective Studies Thyroid Nodule Ultrasonography Doppler Color General Pharmacology Toxicology and Pharmaceutics Thyroiditis Subacute Aged integumentary system General Veterinary business.industry Thyroid Ultrasound Calcinosis Nodule (medicine) General Medicine Middle Aged medicine.disease Carcinoma Papillary Biomedicine medicine.anatomical_structure Predictive value of tests Female Radiology medicine.symptom business |
| Zdroj: | Journal of Zhejiang University SCIENCE B. 13:707-716 |
| ISSN: | 1862-1783 1673-1581 |
| DOI: | 10.1631/jzus.b1100342 |
| Popis: | Objective: To define the roles of gray-scale, color-Doppler ultrasound, and sonoelastography for the assessment of thyroid nodule to determine whether nodule size affects the differential diagnosis of benign and malignant. Methods: A total of 243 consecutive subjects (214 women, 29 men) with 329 thyroid nodules were examined by gray-scale, color-Doppler ultrasound, and sonoelastography in this prospective study. All patients underwent surgery and the final diagnosis was obtained from histopathological examination. Results: Three hundred and twenty-nine nodules (208 benign, 121 malignant) were divided into small (SNs, 5–10 mm, n=137) and large (LNs, >10 mm, n=192) nodules. Microcalcifications were more frequent in malignant LNs than in malignant SNs, but showed no significant difference between benign LNs and SNs. Poorly-circumscribed margins were not significantly different between malignant SNs and LNs, but were less frequent in benign LNs than in benign SNs. Among all nodules, marked intranodular vascularity was more frequent in LNs than in SNs. By comparison, shape ratio of anteroposterior to transverse dimensions (A/T) ≥1 was less frequent in LNs than in SNs. Otherwise, among all nodules, marked hypoechogenicity and elasticity score of 4–6 showed no significant difference between LNs and SNs. Conclusions: The predictive values of microcalcifications, nodular margins, A/T ratio, and marked intranodular vascularity depend on nodule size, but the predictive values of echogenicity and elastography do not. |
| Databáze: | OpenAIRE |
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