Synthesis and characterization of zinc oxide nanoparticles using tuber extract of anchote (Coccinia abyssinica (Lam.) Cong.) for antimicrobial and antioxidant activity assessment
| Autor: | Aschalew Tadesse, Tura Safawo, B. V. Sandeep, Sudhakar Pola |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Coccinia abyssinica
Chemistry DPPH lcsh:RM1-950 technology industry and agriculture Pharmaceutical Science chemistry.chemical_element Nanoparticle 02 engineering and technology Zinc 010402 general chemistry 021001 nanoscience & nanotechnology 01 natural sciences 0104 chemical sciences chemistry.chemical_compound lcsh:Therapeutics. Pharmacology Transmission electron microscopy Internal Medicine Pharmacology (medical) Particle size Fourier transform infrared spectroscopy 0210 nano-technology Spectroscopy Biotechnology Nuclear chemistry |
| Zdroj: | OpenNano, Vol 3, Iss, Pp 56-63 (2018) |
| ISSN: | 2352-9520 |
| Popis: | Coccinia abyssinica (C. abyssinica) tuber extract assisted biosynthesized Zinc oxide nanoparticles (ZnO Nps) were characterized using UV-visible spectroscopy, X-ray diffraction (XRD), Fourier transform infrared (FTIR) spectroscopy, field emission scanning electron microscopy (FESEM) and transmission electron microscopy (TEM). Blue shift of absorptional peak to 365 nm indicated formation of ZnO Nps. X-ray diffraction showed well defined peak characteristic of the Nps. FESEM and TEM image revealed the synthesized nanoparticles has a hexagonal shape and the average particle size was 10.4 nm. The antimicrobial activities of the synthesized ZnO Nps were tested using well diffusion assay and Staphylococcus aureus (MTCC-3160) was found to be the most sensitive against synthesized ZnO Nps whereas, least sensitivity was exhibited by Salmonella typhimurium (MTCC-1251).Free radical scavenging capacity of ZnO Nps were assessed using 2,2–diphenyl-1-picrylhydrazylhydrate (DPPH) assay, with varying ZnO Nps concentration, which showed scavenging activity with IC50 = 127.74 μg /mL. Keywords: ZnO nanoparticles, Coccinia abyssinica, Antimicrobial, Antioxidant, Inhibition zone |
| Databáze: | OpenAIRE |
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