Evaluation of the Merlin, Micronaut System for Automated Antimicrobial Susceptibility Testing of Pseudomonas aeruginosa and Burkholderia Species Isolated from Cystic Fibrosis Patients
| Autor: | H. Weissbrodt, Susanne Häussler, Ziesing S, L. Hoy, Rademacher G |
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| Rok vydání: | 2003 |
| Předmět: |
Male
Microbiology (medical) food.ingredient Cystic Fibrosis Burkholderia Microbial Sensitivity Tests medicine.disease_cause Sensitivity and Specificity Microbiology Agar dilution Automation food Drug Resistance Bacterial medicine Humans Agar Pseudomonas Infections Antibacterial agent Bacteriological Techniques biology Pseudomonas aeruginosa business.industry Broth microdilution General Medicine Antimicrobial biology.organism_classification Anti-Bacterial Agents Infectious Diseases Female business Pseudomonadaceae |
| Zdroj: | European Journal of Clinical Microbiology & Infectious Diseases. 22:496-500 |
| ISSN: | 1435-4373 0934-9723 |
| Popis: | Since accurate antimicrobial susceptibility testing of bacterial cystic fibrosis isolates is known to be problematic and an optimal in vitro testing method has not yet been evaluated, the study presented here was conducted to compare the performance of the reference agar dilution method and broth microdilution with a commercially available automated susceptibility test system (Merlin; Micronaut, Germany). In this pilot study, the susceptibility of 70 clinical strains of Pseudomonas aeruginosa and Burkholderia cepacia-like organisms to nine antimicrobial agents was tested using these methods. Susceptibility results generated by broth microdilution (both automated and according to the National Committee for Clinical Laboratory Standards recommendations) were demonstrated to be of good reproducibility, and they compared favourably to the time- and material-consuming standard agar dilution reference method, especially after a prolonged incubation time (48 h). |
| Databáze: | OpenAIRE |
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