Vitamin D Deficiency in Patients with Diabetes in French Guiana: Epidemiology and Relation with Microvascular and Macrovascular Complications
| Autor: | Elise Girard, Mickael Massicard, Magalie Demar, Aniza Fahrasmane, Diana Okambabelle, Antoine Adenis, Liliane Thelusme, Mathieu Nacher, Kinan Drak Alsibai, Bertrand De Toffol, John Bukasa-Kakamba, Nadia Sabbah, Jean M. Aurelus, Raissa Bekima |
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| Rok vydání: | 2021 |
| Předmět: |
Adult
Male medicine.medical_specialty Diabetic Cardiomyopathies vitamin D deficiency Article Nephropathy Cohort Studies Angina chemistry.chemical_compound angina pectoris Internal medicine Diabetes mellitus Diabetes Mellitus Prevalence medicine Vitamin D and neurology Humans diabetes complications French Guiana TX341-641 Vitamin D Glycated Hemoglobin Diabetic Retinopathy Nutrition and Dietetics Nutrition. Foods and food supply business.industry Middle Aged medicine.disease chemistry Cohort Female Glycated hemoglobin business Polyneuropathy Food Science |
| Zdroj: | Nutrients, Vol 13, Iss 4302, p 4302 (2021) Nutrients Nutrients; Volume 13; Issue 12; Pages: 4302 |
| ISSN: | 2072-6643 |
| DOI: | 10.3390/nu13124302 |
| Popis: | Vitamin D (VD) insufficiency is common among patients with diabetes in French Guiana. The study aimed to evaluate the prevalence of VD deficiency in the different type of diabetes encountered and to analyze the relationship between VD deficiency and diabetes complications. Methods: An observational study was conducted between May 2019 and May 2020 in French Guiana, based on data from the CODIAM study (Diabetes Cohort in French Amazonia), describing the characteristics of patients with diabetes mellitus. Among 600 patients enrolled with diabetes, 361 had an available VD assay. Results: The mean 25(OH)VD (hydroxycalciferol) level was 27.9 ng/mL. The level of VD was inversely proportional to the HbA1c (glycated hemoglobin) level. Patients with angina pectoris had a greater proportion of deficiencies VD < 20 ng/mL than those without angina. By contrast, patients with retinopathy had higher vitamin D concentrations than those without retinopathy. There was no association between vitamin D and arteriopathy, stroke, nephropathy and polyneuropathy. VD deficiency was more frequent in women, and in patients with a high school education. Conclusion: The prevalence of VD deficiency was high in patients with diabetes in French Guiana, emphasizing the importance of VD supplementation. |
| Databáze: | OpenAIRE |
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