The predictive value of platelet function point-of-care tests for postoperative blood loss and transfusion in routine cardiac surgery: a systematic review
| Autor: | Boško Skorić, Marko Boban, Mate Petricevic, Krešimir Kolić, Bojan Biocina, Davor Miličić, Hrvoje Gasparovic, Ante Lekić, Tomislav Kopjar |
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| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
Pulmonary and Respiratory Medicine
Excessive Bleeding medicine.medical_specialty Blood transfusion Platelet Function Tests Point-of-Care Systems medicine.medical_treatment Postoperative Hemorrhage law.invention law Cardiopulmonary bypass Humans Medicine Blood Transfusion Platelet Cardiac Surgical Procedures Coronary Artery Bypass Perioperative Period Monitoring Physiologic business.industry blood transfusion blood coagulation/anticoagulation coronary artery bypass grafts surgery Perioperative medicine.disease Cardiac surgery Discontinuation Bleeding diathesis Anesthesia Surgery Cardiology and Cardiovascular Medicine business Forecasting |
| DOI: | 10.1055/s-0034-1378191 |
| Popis: | Excessive bleeding after cardiopulmonary bypass (CPB) operations remains to be a persistent problem and weak platelet function certainly contributes to bleeding diathesis. Antiplatelet therapy (APT) is an integral component of perioperative management in patients undergoing cardiac surgery procedures, both with and without use of CPB. In addition to individual variability in platelet function, different preoperative APT administration/discontinuation management further affects platelet function, which in turn may reflect bleeding tendency. However, the impact of drug-induced platelet inhibition on early postoperative bleeding extent remains difficult to predict. Herein, we reviewed the available evidence on the association between platelet function testing values and the extent of bleeding and transfusion requirements in early perioperative period. Currently, the association between platelet function measured by ex vivo assay and the occurrence of bleeding events remains uncertain. The intent of this review is to provide comprehensive literature insight into published evidence, investigating the possibility of platelet function tests to predict bleeding extent as well as transfusion requirements in cardiac surgery patients. |
| Databáze: | OpenAIRE |
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