ANTISPERM ANTIBODIES IN CRYPTORCHIDISM BEFORE AND AFTER SURGERY
| Autor: | Daniela Pasquali, Gianni Cobellis, Giovanni Angelone, Antonio Bellastella, Dario Esposito, Antonella Valente, Alfredo Cuomo, Antonello Martone, G. Paolo Fioretti, Alfonso Papparella, Francesco Orio, Antonio Agostino Sinisi |
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| Přispěvatelé: | Sinisi, Antonio Agostino, Pasquali, Daniela, Papparella, Alfonso, Valente, A, Orio, F, Esposito, D, Cobellis, G, Cuomo, A, Angelone, G, Martone, A, Fioretti, Gp, Bellastella, A. |
| Rok vydání: | 1998 |
| Předmět: |
Male
medicine.medical_specialty Adolescent medicine.medical_treatment Urology Semen Preoperative care Immunopathology Cryptorchidism Preoperative Care medicine Humans Orchiopexy Prospective Studies Stage (cooking) Prospective cohort study Child Autoantibodies Gynecology Postoperative Care biology business.industry Infant Spermatozoa Surgery El Niño Child Preschool biology.protein Antibody business |
| Zdroj: | The Journal of Urology. :1834-1837 |
| ISSN: | 0022-5347 |
| DOI: | 10.1097/00005392-199811000-00068 |
| Popis: | PURPOSE: We verified the prevalence of serum antisperm antibodies at diagnosis in a large group of cryptorchid boys, and determined whether it may be influenced by orchiopexy. MATERIALS AND METHODS: We prospectively evaluated serum antisperm antibodies in 186 and 23 boys 0.67 to 14.25 years old with unilateral and bilateral cryptorchidism, respectively, before, and 3, 12 and 24 months after surgery. At diagnosis Tanner stage was 1 and 2 or 3 in 188 and 21 cases, respectively. During the 2-year followup 23 boys entered puberty. A total of 111 normal prepubertal (Tanner stage 1) and 54 pubertal (Tanner stage 2 or 3) boys served as controls. Antisperm antibodies were detected using the tray agglutination and indirect immunobead tests. RESULTS: At diagnosis 29 cryptorchid boys (13.8%) were antisperm antibody positive, including 21 of the 188 prepubertal (11.1%) and 8 of the 21 pubertal (38%) boys (significantly different, chi-square test p |
| Databáze: | OpenAIRE |
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