Existing comorbidities in people with osteoarthritis: a retrospective analysis of a population-based cohort in Alberta, Canada
| Autor: | Peter Faris, Xiaoxiao Liu, Claire E.H. Barber, Tom Noseworthy, Jason Werle, Cheryl Barnabe, Lisa M. Lix, Karen Yee, Dianne Mosher, Deborah A. Marshall |
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| Rok vydání: | 2019 |
| Předmět: |
Male
Databases Factual Prevalence Comorbidity Alberta Pulmonary Disease Chronic Obstructive 0302 clinical medicine Health care Medicine 030212 general & internal medicine Child Depression (differential diagnoses) Original Research Aged 80 and over education.field_of_study COPD Depression General Medicine Middle Aged 3. Good health Child Preschool Female Public Health Adult hypertension Adolescent Population 03 medical and health sciences Young Adult Age Distribution Ambulatory care Osteoarthritis Humans Sex Distribution education Aged Retrospective Studies business.industry Infant Newborn Infant administrative health data Retrospective cohort study medicine.disease business 030217 neurology & neurosurgery Demography |
| Zdroj: | BMJ Open |
| ISSN: | 2044-6055 |
| Popis: | ObjectivesThe purpose of this study is to estimate the prevalence of comorbidities among people with osteoarthritis (OA) using administrative health data.DesignRetrospective cohort analysis.SettingAll residents in the province of Alberta, Canada registered with the Alberta Health Care Insurance Plan population registry.Participants497 362 people with OA as defined by ‘having at least one OA-related hospitalization, or at least two OA-related physician visits or two ambulatory care visits within two years’.Primary outcome measuresWe selected eight comorbidities based on literature review, clinical consultation and the availability of validated case definitions to estimate their frequencies at the time of diagnosis of OA. Sex-stratified age-standardised prevalence rates per 1000 population of eight clinically relevant comorbidities were calculated using direct standardisation with 95% CIs. We applied χ2 tests of independence with a Bonferroni correction to compare the percentage of comorbid conditions in each age group.Results54.6% (n=2 71 794) of people meeting the OA case definition had at least one of the eight selected comorbidities. Females had a significantly higher rate of comorbidities compared with males (standardised rates ratio=1.26, 95% CI 1.25 to 1.28). Depression, chronic obstructive pulmonary disease (COPD) and hypertension were the most prevalent in both females and males after age-standardisation, with 40% of all cases having any combination of these comorbidities. We observed a significant difference in the percentage of comorbidities among age groups, illustrated by the youngest age group (65 years.ConclusionsOur findings highlight the high frequency of comorbidity in people with OA, with depression having the highest age-standardised prevalence rate. Comorbidities differentially affect females, and vary by age. These factors should inform healthcare programme and delivery. |
| Databáze: | OpenAIRE |
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