Anxiety and depression in bronchiectasis: Response to pulmonary rehabilitation and minimal clinically important difference of the Hospital Anxiety and Depression Scale

Autor: Suhani Patel, Ruth E Barker, Michael R. Loebinger, William D.-C. Man, Robert Wilson, Samantha S.C. Kon, Sarah Jones, Jessica A. Walsh, Stephanie C Wynne, Claire M. Nolan, Julius Cairn
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Pulmonary and Respiratory Medicine
Male
medicine.medical_specialty
bronchiectasis
medicine.medical_treatment
Respiratory System
Anxiety
Hospital Anxiety and Depression Scale
Severity of Illness Index
03 medical and health sciences
Pulmonary Disease
Chronic Obstructive

0302 clinical medicine
Internal medicine
Surveys and Questionnaires
London
Outcome Assessment
Health Care

Medicine
Humans
Pulmonary rehabilitation
030212 general & internal medicine
1102 Cardiorespiratory Medicine and Haematology
Depression (differential diagnoses)
Psychiatric Status Rating Scales
COPD
Original Paper
Bronchiectasis
business.industry
Minimal clinically important difference
minimal clinically important difference
1103 Clinical Sciences
Middle Aged
medicine.disease
pulmonary rehabilitation
Mood
Treatment Outcome
030228 respiratory system
depression
Quality of Life
Female
medicine.symptom
business
Zdroj: Chronic Respiratory Disease
Popis: The aims of the study were to evaluate the responsiveness of Hospital Anxiety and Depression Scale-Anxiety (HADS-A) subscale and HADS-Depression (HADS-D) subscale to pulmonary rehabilitation (PR) in patients with bronchiectasis compared to a matched group of patients with chronic obstructive pulmonary disease (COPD) and provide estimates of the minimal clinically important difference (MCID) of HADS-A and HADS-D in bronchiectasis. Patients with bronchiectasis and at least mild anxiety or depression (HADS-A ≥ 8 or/and HADS-D ≥ 8), as well as a propensity score-matched control group of patients with COPD, underwent an 8-week outpatient PR programme (two supervised sessions per week). Within- and between-group changes were calculated in response to PR. Anchor- and distribution-based methods were used to estimate the MCID. HADS-A and HADS-D improved in response to PR in both patients with bronchiectasis and those with COPD (median (25th, 75th centile)/mean (95% confidence interval) change: HADS-A change: bronchiectasis −2 (−5, 0), COPD −2 (−4, 0); p = 0.43 and HADS-D change: bronchiectasis −2 (−2 to −1), COPD −2 (−3 to −2); p = 0.16). Using 26 estimates, the MCID for HADS-A and HADS-D was −2 points. HADS-A and HADS-D are responsive to PR in patients with bronchiectasis and symptoms of mood disorder, with an MCID estimate of −2 points.
Databáze: OpenAIRE