Conjugates of glycosylated steroids and polyamines as novel nonviral gene delivery systems
| Autor: | C. Longley, Babu Suresh D, N. Kogan, H. Axelrod, R. Kakarla, Suzanne Walker, L. Wierichs, M. Sofia, S. Midha |
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| Rok vydání: | 1995 |
| Předmět: |
Dna delivery
Drug Carriers Chemistry General Neuroscience Genetic enhancement Phosphatidylethanolamines DNA Recombinant Gene Transfer Techniques Gene delivery beta-Galactosidase Molecular biology General Biochemistry Genetics and Molecular Biology Transmembrane protein History and Philosophy of Science Biochemistry Genes Reporter Amphiphile Chlorocebus aethiops Polyamines Animals Steroids Drug transport Conjugate Cell Line Transformed |
| Zdroj: | Annals of the New York Academy of Sciences. 772 |
| ISSN: | 0077-8923 |
| Popis: | We have designed novel glycosteroid-polyamines for transmembrane DNA delivery based on amphiphilic drug transport agents. These glycosteroid-based agents show promise as viable DNA delivery technology for gene therapy. |
| Databáze: | OpenAIRE |
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