Effects of long-term cadmium exposure on trehalose metabolism, growth, and development of Aedes albopictus (Diptera: Culicidae)
| Autor: | Qiwei Wang, Ying Wei, Lingyuan Yu, Shaohua Wang, Yanjuan Ding, Bin Tang, Xumin Chen, Shigui Wang |
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| Rok vydání: | 2020 |
| Předmět: |
Aedes albopictus
Health Toxicology and Mutagenesis 0211 other engineering and technologies Trehalase activity chemistry.chemical_element Blood sugar 02 engineering and technology 010501 environmental sciences 01 natural sciences chemistry.chemical_compound Aedes Animals Food science Trehalase Ovum 0105 earth and related environmental sciences 021110 strategic defence & security studies Cadmium biology Hatching fungi Pupa Public Health Environmental and Occupational Health Trehalose General Medicine biology.organism_classification Pollution chemistry Larva Female Energy source Water Pollutants Chemical |
| Zdroj: | Ecotoxicology and Environmental Safety. 204:111034 |
| ISSN: | 0147-6513 |
| DOI: | 10.1016/j.ecoenv.2020.111034 |
| Popis: | Trehalose is the major blood sugar in insects; it not only serves as an energy source but also plays important roles in physiological responses to adverse conditions. However, only a few studies have explored the effects of heavy metal exposure stress on trehalose metabolism in insects. Therefore, in this study, we examined the effects of cadmium stress on changes in trehalose metabolism in Aedes albopictus. Three concentrations of cadmium (0.005, 0.01, and 0.1 mg/L) were selected for evaluation of long-term stress in Ae. albopictus (from eggs to adults); Ae. albopictus in double-distilled water was used as the control group. The trehalose and glucose contents, trehalase activity, and trehalose metabolism-related gene expression were determined. The effects of long-term cadmium exposure on growth, development, and reproduction were also assessed. Trehalose contents were increased, whereas glucose contents and trehalase activity were decreased in Ae. albopictus following long-term exposure to low concentrations of cadmium compared with those in untreated individuals. Moreover, the expression of trehalose-6-phosphate synthase was upregulated, and that of trehalase was downregulated, indicating that Ae. albopictus may enhance trehalose synthesis to resist cadmium stress. Cadmium exposure also caused Ae. albopictus individuals to become smaller with a longer developmental duration, whereas both reproduction and hatching rates of the offspring were decreased compared with those in the control group. Our findings demonstrated that cadmium exposure affected the morphology, physiology, and biochemistry of Ae. albopictus. These findings also confirmed the role of trehalose in the response of Ae. albopictus to cadmium stress, providing insights into the effects of heavy metal stress on trehalose metabolism in an insect model. |
| Databáze: | OpenAIRE |
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