A Nonfunctional Halogenase Masquerades as an Aromatizing Dehydratase in Biosynthesis of Pyrrolic Polyketides by Type I Polyketide Synthases

Autor:	Dongqi Yi, Dhirendra Niroula, Will R. Gutekunst, Joyce E. Loper, Qing Yan, Vinayak Agarwal
Rok vydání:	2022
Předmět:	Multigene Family Polyketides Molecular Medicine General Medicine Biochemistry Polyketide Synthases Hydro-Lyases Anti-Bacterial Agents
Zdroj:	ACS chemical biology. 17(6)
ISSN:	1554-8937
Popis:	The bacterial modular type I polyketide synthases (PKSs) typically furnish nonaromatic lactone and lactam natural products. Here, by the complete
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::454cba45cb9fb277ddf1a9de6ddd27e9 https://pubmed.ncbi.nlm.nih.gov/35675261 Zobrazit plný text záznamu