Early Events in Herpes Simplex Virus Infection: a Radioautographic Study
| Autor: | Natale Tomassini, Klaus Hummeler, Barbara A. Zajac |
|---|---|
| Rok vydání: | 1969 |
| Předmět: |
Simplexvirus
food.ingredient viruses Immunology Biology Kidney Tritium Virus Replication Microbiology Virus Cell Line chemistry.chemical_compound food Cricetinae Virology Animal Viruses medicine Animals Cell Nucleus Chromatin Microscopy Electron Cell nucleus medicine.anatomical_structure chemistry Viral replication Cell culture Insect Science Autoradiography Thymidine DNA |
| Zdroj: | Journal of Virology. 4:67-74 |
| ISSN: | 1098-5514 0022-538X |
| DOI: | 10.1128/jvi.4.1.67-74.1969 |
| Popis: | The early events in herpes simplex virus infection were studied by means of radio-autography. The virus was rapidly taken up by the host cells and uncoated. Viral deoxyribonucleic acid (DNA) reached the nuclear sites of replication in 15 to 30 min after infection. The viral DNA occasionally associated with chromosomes or condensed chromatin but was more frequently found to be randomly distributed. Viral progeny appeared 3 hr after infection. These particles did not show any particular spatial relationship to the parental DNA. The morphological latent period lasted 2.5 hr. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|