Exposure to particulate matter: Direct and indirect role in the COVID-19 pandemic
| Autor: | Pablo Fdez-Arroyabe, Ignacio Fernández-Olmo, Ana Santurtún, María T. Zarrabeitia, Marina L. Colom, Álvaro del Real |
|---|---|
| Přispěvatelé: | Universidad de Cantabria |
| Rok vydání: | 2022 |
| Předmět: |
Coronavirus disease 2019 (COVID-19)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Air pollution Biology Biochemistry Article law.invention law Environmental health Pandemic Humans Pandemics General Environmental Science SARS-CoV-2 fungi Suspended particles COVID-19 Outbreak Particulates Transmission (mechanics) RNA Viral Particulate Matter Vector Particulate matter Covid-19 Viral load ACE-2 |
| Zdroj: | Environmental Research Environmental Research, 2022, 206, 112261 UCrea Repositorio Abierto de la Universidad de Cantabria Universidad de Cantabria (UC) |
| ISSN: | 0013-9351 |
| DOI: | 10.1016/j.envres.2021.112261 |
| Popis: | Knowing the transmission factors and the natural environment that favor the spread of a viral infection is crucial to stop outbreaks and develop effective preventive strategies. This work aims to evaluate the role of Particulate Matter (PM) in the COVID-19 pandemic, focusing especially on that of PM as a vector for SARS-CoV-2. Exposure to PM has been related to new cases and to the clinical severity of people infected by SARS-CoV-2, which can be explained by the oxidative stress and the inflammatory response generated by these particles when entering the respiratory system, as well as by the role of PM in the expression of ACE-2 in respiratory cells in human hosts. In addition, different authors have detected SARS-CoV-2 RNA in PM sampled both in outdoor and indoor environments. The results of various studies lead to the hypothesis that the aerosols emitted by an infected person could be deposited in other suspended particles, sometimes of natural but especially of anthropogenic origin, that form the basal PM. However, the viability of the virus in PM has not yet been demonstrated. Should PM be confirmed as a vector of transmission, prevention strategies ought to be adapted, and PM sampling in outdoor environments could become an indicator of viral load in a specific area. “This work has been carried out within the framework of the project “Air pollution and COVID-19: what can we learn from this pandemic?” of the Call for Grants from the BBVA Foundation to Scientific Research Teams in SARS-CoV-2 and COVID-19, in the area of Ecology and Veterinary Medicine” |
| Databáze: | OpenAIRE |
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