Higher expression of circulating miR-182 as a novel biomarker for breast cancer
| Autor: | Huihui Zhou, Baofa Jiang, Hai‑Tao Gong, Huan‑Tai Wang, Chun‑Lei Lv, Shu‑Yang Xie, Bao‑Feng Li, Ping‑Yu Wang, Xin-Xin Li |
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| Rok vydání: | 2013 |
| Předmět: |
Cancer Research
medicine.medical_specialty Oncogene diagnosis business.industry Estrogen receptor Cancer Articles medicine.disease Molecular medicine breast cancer Breast cancer Endocrinology Real-time polymerase chain reaction Oncology miR-182 Internal medicine Progesterone receptor Immunology gene expression medicine circulating miRNAs Biomarker (medicine) business |
| Zdroj: | Oncology Letters |
| ISSN: | 1792-1082 1792-1074 |
| DOI: | 10.3892/ol.2013.1593 |
| Popis: | MicroRNAs (miRNAs), present in the serum in a stable and reproducible manner, may be used as biomarkers for various diseases. Few studies have previously investigated circulating miRNAs in the peripheral blood of breast cancer (BC) patients. To identify the role of serum miR-182 levels in BC, the present study detected miR-182 levels in the serum of 46 BC patients and 58 controls, by quantitative PCR. The results showed that the serum miR-182 levels in BC patients were significantly higher compared with the serum of healthy controls (P |
| Databáze: | OpenAIRE |
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