In Vivo Measurement of Cervical Elasticity on Pregnant Women by Torsional Wave Technique: A Preliminary Study

Autor: Given Names Deactivated Family Name Deactivated, Paloma Massó, Guillermo Rus, Juan Melchor, Antonio Manuel Callejas Zafra, Francisca Molina
Rok vydání: 2019
Předmět:
Adult
Torsion Abnormality
medicine.medical_specialty
torsional wave
medicine.medical_treatment
Cervical stiffness
Gestational Age
Cervix Uteri
lcsh:Chemical technology
Biochemistry
Article
Cervix
030218 nuclear medicine & medical imaging
Analytical Chemistry
03 medical and health sciences
0302 clinical medicine
Pregnancy
In vivo
cervix
medicine
Humans
lcsh:TP1-1185
Labor
Induced
Electrical and Electronic Engineering
Elasticity (economics)
Instrumentation
cervical stiffness
030219 obstetrics & reproductive medicine
Torsional wave
business.industry
Obstetrics
Gestational age
Stiffness
medicine.disease
Elasticity
Atomic and Molecular Physics
and Optics
Cross-Sectional Studies
medicine.anatomical_structure
Labor induction
Elasticity Imaging Techniques
Gestation
Female
pregnancy
medicine.symptom
business
Cervical Ripening
Zdroj: Sensors, Vol 19, Iss 15, p 3249 (2019)
Digibug. Repositorio Institucional de la Universidad de Granada
instname
Sensors
Volume 19
Issue 15
Sensors (Basel, Switzerland)
ISSN: 1424-8220
DOI: 10.3390/s19153249
Popis: A torsional wave (TW) sensor prototype was employed to quantify stiffness of the cervix in pregnant women. A cross-sectional study in a total of 18 women between 16 weeks and 35 weeks + 5 days of gestation was performed. The potential of TW technique to assess cervical ripening was evaluated by the measurement of stiffness related to gestational age and cervical length. Statistically significant correlations were found between cervical stiffness and gestational age (R2 = 0.370, p = 0.0074, using 1 kHz waves and R2 = 0.445, p = 0.0250, using 1.5 kHz waves). A uniform decrease in stiffness of the cervical tissue was confirmed to happen during the complete gestation. There was no significant correlation between stiffness and cervical length. A stronger association between gestational age and cervical stiffness was found compared to gestational age and cervical length correlation. As a conclusion, TW technique is a feasible approach to objectively quantify the decrease of cervical stiffness related to gestational age. Further research is required to evaluate the application of TW technique in obstetric evaluations, such as prediction of preterm delivery and labor induction failure.
This research was funded by the Ministry of Education grant numbers DPI2017-83859-R, DPI2014-51870-R and UNGR15-CE-3664, Ministry of Health grant numbers DTS15/00093 and PI16/00339, and Junta de Andalucía grant numbers, PI-0107-2017 and PIN-0030-2017.
Databáze: OpenAIRE
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