Effect of Dietary Supplementation of Spirulina (Arthrospira Platensis) and Thyme (Thymus Vulgaris) on Serum Biochemistry, Immune Response and Antioxidant Status of Rabbits
| Autor: | Erika Balogh-Zándoki, Gábor Milisits, Tamás Tuboly, Krisztián Balogh, Zsolt Matics, Gábor Tornyos, Alessandro Dal Bosco, Zsolt Szendrő, Dóra Hafner, Melinda Kovács, Antonella Dalle Zotte, Zsolt Gerencsér, Miklós Mézes |
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| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
030109 nutrition & dietetics biology Thymus vulgaris 0402 animal and dairy science Albumin Serum albumin Spirulina thyme serum biochemistry immune response antioxidant status Blood sugar 04 agricultural and veterinary sciences biology.organism_classification antioxidant status 040201 dairy & animal science Blood proteins immune response 03 medical and health sciences serum biochemistry Animal science Blood chemistry thyme Immunology Spirulina biology.protein Weaning Spirulina (dietary supplement) |
| Zdroj: | Annals of Animal Science. 16:181-195 |
| ISSN: | 2300-8733 |
| DOI: | 10.1515/aoas-2015-0059 |
| Popis: | Growing rabbits’ (42 rabbits/group, 3 rabbits/cage, 14 cages/treatment) diet was supplemented with 5% Spirulina (Arthrospira platensis) and 3% thyme (Thymus vulgaris L.) powder single (S or T) and in combination (ST) between 35 and 77 days of age. On day 0 (weaning at 35 days of age) 14 rabbits were vaccinated with 100 μg/animal ovalbumin to provoke immune response. Blood samples were taken on days 0, 14, 28 and 42 of the experimental period. Sampling dates significantly influenced total protein, albumin, glucose, cholesterol, urea, creatinine concentration and enzyme (AST, ALT, GGT) activities, with a significant age × diet interaction in the case of TP and CREA. There was a significant increase in ALT (+45 and 74%) and GGT (+87 and 102%) activity after immunisation. While Spirulina and thyme significantly ameliorated the rise in AST activity, their effect was inefficient in the case of GGT. Spirulina, both single and in combination showed a tendency in higher IgG level as compared to control (P0.05). Higher MDA concentration was measured in the red blood cells of S, T and ST animals, while no other significant diet effect on the antioxidant parameters was detected, however, significant sampling date × diet interaction was found in the case of GPx activity. Plasma GGT (increase by 19-66%) was inversely associated with GSH (decrease by 66-113%) between days 0 to 42 of the experimental period (r=-0.57, P |
| Databáze: | OpenAIRE |
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