Tardive dyskinesia and glucid metabolism
| Autor: | Olivier Blanc, Jacques Mouret, Thierry Hueber, Pierre-Michel Llorca, Philippe Lemoine, Georges Brousse, Alexandre Méary, Bernard Lachaux |
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| Rok vydání: | 2007 |
| Předmět: |
Adult
Blood Glucose Male Dyskinesia Drug-Induced medicine.medical_specialty medicine.drug_class Population Carbohydrate metabolism Tardive dyskinesia Risk Factors Dopamine Internal medicine Diabetes mellitus otorhinolaryngologic diseases medicine Humans Pharmacology (medical) education Glucose Metabolism Disorders Analysis of Variance education.field_of_study Metabolism Postprandial Period medicine.disease Typical antipsychotic Abnormal involuntary movement Psychiatry and Mental health Endocrinology Neurology Schizophrenia Female Neurology (clinical) Psychology Antipsychotic Agents medicine.drug |
| Zdroj: | Human Psychopharmacology: Clinical and Experimental. 22:373-380 |
| ISSN: | 1099-1077 0885-6222 |
| Popis: | A role of insulin-dependent diabetes in the onset of tardive dyskinesia has been reported and relies on weak physiopathological evidence. Objective To study the relationship between the occurrence of tardive dyskinesia and variations in glucose levels in a population of patients under typical antipsychotic treatment. Methods Sixty-nine patients with a schizophrenic disorder and who had been receiving continuous neuroleptic treatment for at least 2 years were included. Tardive dyskinesias were assessed by the Abnormal Involuntary Movements Scale (AIMS) and glucose levels by glucose oxidase method. Results No significant differences in values of fasting glucose (FG) levels, post-prandial glucose (PPG) levels and glycosylated haemoglobin between the groups with and without tardive dyskinesia were found. In the sub-group with normal FG, comparison of post-prandial delta glucose levels (difference between PPG and FG) between the two group with and without tardive dyskinesia showed a significant difference (p |
| Databáze: | OpenAIRE |
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