Clinical Phenotypes in NSAID-Induced Urticaria/Angioedema
| Autor: | Joaquin Quiralte-Castillo, Joaquín Quiralte, María del Robledo Ávila, Stefan Cimbollek |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty business.industry InformationSystems_INFORMATIONSTORAGEANDRETRIEVAL Angioneurotic oedema Phenotype Dermatology digestive system diseases 03 medical and health sciences 030104 developmental biology 0302 clinical medicine 030228 respiratory system Medicine business GeneralLiterature_REFERENCE(e.g. dictionaries encyclopedias glossaries) |
| DOI: | 10.5772/intechopen.96718 |
| Popis: | The skin clinical phenotypes of nonsteroidal anti-inflammatory drug (NSAID) hypersensitivity (NH) are very heterogeneous with several syndromes after NSAID intake, which include different symptoms, different organ involvement and different associated concomitant diseases and possibly different underlying pathophysiology and mechanisms. Making a correct diagnosis in NH is an exciting journey for any allergist. Thus, to classify these diseases properly will be pivotal for appropriate diagnostic and management strategy. Treatment modalities are depending on the clinical phenotypes of NH and they will embrace for each patient: the avoidance of culprit NSAID, the finding of well-tolerated NSAID and in certain cases, desensitization procedures when the NSAID treatment was absolutely needed as well as the control of associated diseases such as spontaneous chronic urticarial or allergic respiratory diseases. This review updates the recent evidence of classification, diagnostic strategies, and management of skin NSAID hypersensitivity reactions. |
| Databáze: | OpenAIRE |
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