A prospective evaluation of thromboelastometry (ROTEM) to identify acute traumatic coagulopathy and predict massive transfusion in military trauma patients in Afghanistan

Autor:	Thomas Scorer, Zachary Wright, Ian J. Stewart, Chriselda G. Fedyk, Hana Kwan, Kelly D. Heegard, Jared Cohen, Christopher E. White, Kevin K. Chung, Jonathan A. Sosnov, Andrew P. Cap, Heather F. Pidcoke
Rok vydání:	2019
Předmět:	Adult Male medicine.medical_specialty Adolescent Clinical Decision-Making Immunology Hemorrhage 030204 cardiovascular system & hematology Hospitals Military Models Biological Prospective evaluation Acute traumatic coagulopathy 03 medical and health sciences 0302 clinical medicine Predictive Value of Tests Humans Immunology and Allergy Medicine International Normalized Ratio Prospective Studies Prospective cohort study Fibrinolysis inhibitor Afghan Campaign 2001 business.industry Afghanistan Hematology Blood Coagulation Disorders Massive transfusion Thrombelastography Clinical trial Thromboelastometry Military Personnel Predictive value of tests Emergency medicine Wounds and Injuries business 030215 immunology
Zdroj:	Transfusion. 59:1601-1607
ISSN:	1537-2995 0041-1132
DOI:	10.1111/trf.15176
Popis:	BACKGROUND Hemorrhage is the leading cause of preventable trauma-related mortality and is frequently aggravated by acute traumatic coagulopathy (ATC). Viscoelastic tests such as rotational thromboelastometry (ROTEM) may improve identification and management of ATC. This study aimed to prospectively evaluate changes in ROTEM among combat casualties during the first 24 hours and compare the capabilities of our conventional clotting assay (international normalized ratio [INR], >1.2) to a proposed integrated ROTEM model (INR >1.2 with the addition of tissue factor pathway activation thromboelastometry [EXTEM] A5 ≤35 mm and/or EXTEM LI30
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::449a24de659a05c763486ae01036c83e https://doi.org/10.1111/trf.15176 Zobrazit plný text záznamu Plný text