| Autor: |
Maharana, Santosh, Schlosser, Gerhard |
| Rok vydání: |
2018 |
| DOI: |
10.6084/m9.figshare.6823805 |
| Popis: |
Figure S5. Effects of Eya1 knockdown on NPB markers and other ectodermal TFs. A-J: Expression of PPE (Six1, Sox3), NC (FoxD3), neural plate (Sox3) markers and early ectodermal TFs in dorsal views of neural plate stage Xenopus embryos after injection of Eya1 MO1 + MO2. Anterior is to the bottom. Control side is shown on the left and injected side on the right (as indicated by blue LacZ staining). Arrowheads indicate expression domains on the control side. Reductions (arrows) and increased or ectopic expression domains (asterisks) in the neural (green) and non-neural ectoderm (orange) compared with the control side (arrowheads) are indicated. Green lines indicate broadening of the neural plate and lateral displacement of NPB markers on the injected side (bright green) versus control side (dark green). Insets show alternative phenotypes. K: Summary of regulatory interactions. Arrows indicate requirement of Eya1 for expression of TFs (reduction after Eya1 knockdown). Bars indicate requirement of Eya1 for restriction of expression of TFs (increase after Eya1 knockdown). Faint colors indicate less frequent phenotypes. See Additional file 1: Table S8 for numbers. (PDF 2013 kb) |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
