Quality-of-life outcomes with minimally invasive transforaminal lumbar interbody fusion based on long-term analysis of 304 consecutive patients

Autor: Mick J. Perez-Cruet, G. Zachary White, Sammy A. Yacob, Robert A. Collins, Daniel K. Fahim, Fadumo M. Adbi, Evan M. Begun, Namath S. Hussain, Girish K. Hiremath
Rok vydání: 2013
Předmět:
musculoskeletal diseases
Adult
Male
medicine.medical_specialty
Time Factors
medicine.medical_treatment
patient outcomes
Lumbar vertebrae
Intervertebral Disc Degeneration
Outcomes
minimally invasive transforaminal
Young Adult
Quality of life
Lumbar interbody fusion
medicine
Humans
Minimally Invasive Surgical Procedures
Orthopedics and Sports Medicine
Prospective Studies
Prospective cohort study
Aged
Aged
80 and over

Lumbar Vertebrae
business.industry
Follow up studies
Middle Aged
minimally invasive spine surgery
musculoskeletal system
Surgery
lumbar fusion
Clinical trial
Radiography
lumbar interbody fusion
percutaneous pedicle screws

medicine.anatomical_structure
Spinal Fusion
Treatment Outcome
Spinal fusion
Prospective clinical study
Physical therapy
Quality of Life
Female
Neurology (clinical)
business
Follow-Up Studies
Zdroj: Spine
ISSN: 1528-1159
Popis: Long-term prospective outcomes in patients undergoing minimally invasive transforaminal lumbar interbody fusion (MITLIF) is not well studied. This article is a prospective clinical study to examine short-/long-term outcomes of 304 patients undergoing MITLIF. There were statistically significant clinical outcomes after MITLIF surgery, including spinal fusion and decreased postoperative complications.
Study Design. This was a prospective clinical study that took place in an outpatient spine clinic. Objective. To demonstrate the short-/long-term outcomes from a large cohort of patients undergoing minimally invasive transforaminal lumbar interbody fusion (MITLIF). Summary of Background Data. Long-term prospective outcomes in patients undergoing minimally invasive spinal fusion for debilitating back pain has not been well studied. Methods. Presenting diagnosis was determined from clinical findings and radiographical (radiograph, magnetic resonance image, computed tomographic scan) evaluations preoperatively. Patients were assessed with outcome measures preoperatively, and postoperatively at 2 weeks, 3 months, 6 months, 12 months, 24 months, and annually 2 to 7 years (mean follow-up: 47 mo) final follow-up. The rate of postoperative complications and reoperations at the initial level of MITLIF and adjacent level(s) were followed. Fusion rates were assessed blinded and independently by radiograph. Results. Visual analogue scale scores decreased significantly from 7.0 preoperatively to 3.5 at mean 47-month follow-up. Oswestry Disability Index scores declined from 43.1 preoperatively to 28.2 at mean 47-month follow-up. Short-Form 36 mental component scores increased from 43.8 preoperatively to 49.7 at 47-month follow-up. Short-Form 36 physical component scores increased from 30.6 preoperatively to 39.6 at 47-month follow-up (P < 0.05). Conclusion. This prospectively collected outcomes study shows long-term statistically significant clinical outcomes improvement after MITLIF in patients with clinically symptomatic spondylolisthesis and degenerative disc disease with or without stenosis. MITLIF resulted in a high rate of spinal fusion and very low rate of interbody fusion failure and/or adjacent segment disease requiring reoperation while reducing postoperative complications. Level of Evidence: 3
Databáze: OpenAIRE