Acute Psychogeriatric Inpatient Treatment Improves Neuropsychiatric Symptoms but Impairs the Level of Functioning in Patients with Dementia
| Autor: | Esa Leinonen, Kirsti Suontaka-Jamalainen, Hanna-Mari Alanen, Anneli Pitkänen, Olli Kampman |
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| Rok vydání: | 2015 |
| Předmět: |
Male
medicine.medical_specialty Activities of daily living medicine.drug_class Cognitive Neuroscience medicine.medical_treatment Geriatric Psychiatry Disease Neuropsychological Tests Severity of Illness Index Anxiolytic Alzheimer Disease Internal medicine Activities of Daily Living Severity of illness Humans Medicine Dementia Psychiatry Antipsychotic Aged Aged 80 and over Inpatients business.industry Middle Aged medicine.disease Hospitalization Psychiatry and Mental health Anti-Anxiety Agents Female Geriatrics and Gerontology Alzheimer's disease business Geriatric psychiatry Antipsychotic Agents |
| Zdroj: | Dementia and Geriatric Cognitive Disorders. 40:290-296 |
| ISSN: | 1421-9824 1420-8008 |
| Popis: | Aims: To explore the impact of hospitalization on neuropsychiatric symptoms (NPS) and the level of functioning in patients with dementia. Our aim was also to study the influence of psychotropic medications. Methods: Behavioral disturbances, cognition and functional status of 89 patients were assessed using the Neuropsychiatric Inventory (NPI), Mini-Mental State Examination, Barthel Index, and Alzheimer's Disease Cooperative Study-Activities of Daily Living (ADCSADL). Results: The total NPI score decreased from 34.6 to 19.5 (p < 0.001), and ADL decreased from 32.2 to 21.7 (p < 0.001) during the hospital stay (mean of 44 days). For a change in ADL, only the effect of anxiolytics was significant (p = 0.045). For a change in NPI with antipsychotic and anxiolytic doses and Mini-Mental State Examination as covariates, no significant relationship was found. Conclusion: NPS improved significantly during hospitalization, but neither antipsychotic nor anxiolytic medication use explained this improvement. In patients using anxiolytics, the functional decline was substantial. These results do not support anxiolytic use in demented patients with NPS. |
| Databáze: | OpenAIRE |
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