What lies beneath the surface of the itch in adults?
| Autor: | David Weldon |
|---|---|
| Rok vydání: | 2007 |
| Předmět: |
Adult
Pulmonary and Respiratory Medicine medicine.medical_specialty Drug-Related Side Effects and Adverse Reactions Urticaria Dermatitis Herpetiformis Substance P Skin Diseases Diagnosis Differential Scabies chemistry.chemical_compound Pemphigoid Bullous medicine Humans Psoriasis Immunology and Allergy skin and connective tissue diseases Skin Nerve Fibers Unmyelinated integumentary system Histamine metabolism Tumor Necrosis Factor-alpha business.industry Mental Disorders Pruritus Lateral spinothalamic tract Lichen Planus Somatosensory Cortex General Medicine Somatic sensory cortex Dermatology body regions medicine.anatomical_structure chemistry Anesthesia Itching medicine.symptom business Histamine Chronic pruritus |
| Zdroj: | Allergy and Asthma Proceedings. 28:153-162 |
| ISSN: | 1088-5412 |
| DOI: | 10.2500/aap.2007.28.2942 |
| Popis: | Pruritus is synonymous with itching. Many medical conditions are complicated by chronic pruritus compromising the patient's quality of life. The majority of pruritic stimuli are transmitted through C fibers into the lateral spinothalamic tract and then into the somatic sensory cortex where the itching is detected. Histamine, substance P, and tumor necrosis factor a play significant roles in the perception of pruritus. Medical conditions in adults with significant pruritus will be defined in this review. |
| Databáze: | OpenAIRE |
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