The effect of local anesthetics on the central nervous system toxicity of hyperbaric oxygen
| Autor: | L.J. Krenis, P.L. Liu, S.H. Ngai |
|---|---|
| Rok vydání: | 1971 |
| Předmět: |
Male
Serotonin Lidocaine Dopamine Central nervous system Neuronal membrane Pharmacology Cellular and Molecular Neuroscience Mice Norepinephrine Hyperbaric oxygen Cocaine Central Nervous System Diseases medicine Animals skin and connective tissue diseases Brain Chemistry Hyperbaric Oxygenation business.industry Mechanism (biology) Cns toxicity Oxygen Monoamine neurotransmitter medicine.anatomical_structure Anesthesia Toxicity sense organs business medicine.drug |
| Zdroj: | Neuropharmacology. 10(5) |
| ISSN: | 0028-3908 |
| Popis: | Lidocaine and cocaine in subconvulsant doses protected mice against CNS toxicity during exposure to hyperbaric oxygen. The mechanism of this protection is unknown, as is the mechanism of hyperbaric oxygen toxicity itself, but both may involve changes in the brain monoamine systems, or changes in the excitability of neuronal membranes. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|