Utility of prophylactic antibiotics in pediatric adenoidectomy
| Autor: | P. Peña-García, N. Sastre, J.I. De Diego, S. Sánchez-Carrión, Maria P. Prim |
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| Rok vydání: | 2006 |
| Předmět: |
Male
medicine.medical_specialty Adolescent medicine.drug_class medicine.medical_treatment Antibiotics Bacteremia Adenoid law.invention Adenoidectomy Postoperative Complications Randomized controlled trial Lymphadenitis Risk Factors law Preoperative Care medicine Humans Prospective Studies Antibiotic prophylaxis Child Prospective cohort study business.industry Incidence Infant General Medicine medicine.disease Curettage Anti-Bacterial Agents Surgery medicine.anatomical_structure Otorhinolaryngology Child Preschool Pediatrics Perinatology and Child Health Female business |
| Zdroj: | International Journal of Pediatric Otorhinolaryngology. 70:1275-1281 |
| ISSN: | 0165-5876 |
| DOI: | 10.1016/j.ijporl.2006.01.007 |
| Popis: | To determine the utility of prophylactic antibiotics in non-risk pediatric patients undergoing adenoidectomy.We performed a prospective, controlled, randomized, and double-blind study on patients under 14 years of age, scheduled for adenoidectomy who accomplished the following criteria: absence of immunosuppressive and/or cardiovascular risk factors, no antimicrobial therapy for at least 15 days prior to operation, and no fever 1 week before surgery. Venous blood samples for culture were obtained at 30s and 20 min after the curettage of adenoidal tissue. Likewise, immediate and delayed complications were registered in all cases. The usefulness of prophylaxis was analyzed according to three major standpoints: bacteremia, immediate complications, and delayed complications.One-hundred one patients fulfilled the inclusion criteria and were included in the study. Fifty-one children received prophylaxis and the remainder did not. In the non-prophylactic group incidence of bacteremia at 30s was significantly higher than in the prophylactic group (32.7% versus 4.0%) (p0.001). Neither bacteremia at 20 min, nor immediate or delayed complications showed statistical differences between both treatment groups.Preoperative antimicrobial prophylaxis in pediatric adenoidectomy did not offer advantages preventing complications in non-risk patients. Only bacteremia that occurs 30s after the curettage of adenoid tissue is reduced with the employment of prophylactic antibiotics. |
| Databáze: | OpenAIRE |
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