Stille, Heck, and Sonogashira coupling and hydrogenation catalyzed by porous-silica-gel-supported palladium in batch and flow
| Autor: | Kiyoshi Matsuyama, Kiyonari Shiosaki, Yosuke Ashikari, Chiemi Fujita, Hongzhi Bai, Aiichiro Nagaki, Mai Ishibashi, Kei Maekawa |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Materials science
Renewable Energy Sustainability and the Environment Silica gel Health Toxicology and Mutagenesis General Chemical Engineering heterogeneous catalyst Sonogashira coupling chemistry.chemical_element stille coupling Industrial and Manufacturing Engineering Stille reaction Catalysis chemistry.chemical_compound Chemistry Fuel Technology chemistry Polymer chemistry Environmental Chemistry flow reaction hydrogenation Porosity QD1-999 Palladium |
| Zdroj: | Green Processing and Synthesis, Vol 10, Iss 1, Pp 722-728 (2021) |
| ISSN: | 2191-9550 |
| Popis: | Owing to their recyclability, heterogeneous transition metal catalysts represent a means of conserving depletable resources for the synthesis of pharmaceutical, agricultural, and functional chemicals. We recently developed a novel heterogeneous palladium catalyst and demonstrated its synthetic availability for Suzuki–Miyaura cross-coupling. Herein, we report the further application of the present catalyst to cross-coupling reactions in batch and flow, as well as a hydrogenative reduction reaction in flow. We demonstrate the flow synthesis for useful material, a liquid crystal, and a 1 h sequential operation of the coupling reaction and hydrogenation reaction. |
| Databáze: | OpenAIRE |
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