Combination of EP4 antagonist and checkpoint inhibitors promotes anti-tumor effector T cells in preclinical tumor models
Autor: | Diana I. Albu, Mary Woodall-Jappe, Natalie C. Twine, Xingfeng Bao, Kuan-Chun Huang, Jiayi Wu, Kenichi Nomoto |
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Rok vydání: | 2015 |
Předmět: |
Pharmacology
Antitumor activity Cancer Research business.industry Effector Immune checkpoint inhibitors medicine.medical_treatment Immunology Antagonist Cancer Bioinformatics medicine.disease Immune checkpoint Oncology Cancer immunotherapy Poster Presentation Cancer research Molecular Medicine Immunology and Allergy Medicine business Receptor |
Zdroj: | Journal for Immunotherapy of Cancer |
ISSN: | 2051-1426 |
DOI: | 10.1186/2051-1426-3-s2-p350 |
Popis: | Meeting abstracts Immunotherapies targeting the immune checkpoint receptors have shown great promise for a subset of cancer patients. However, robust and safe combination therapies are still needed to increase the benefit of cancer immunotherapy and bring it to broader patient populations. We have |
Databáze: | OpenAIRE |
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