Antidepressants Are the Most Commonly Discontinued Psychotherapeutic Medications in Pregnancy
| Autor: | Benjamin J. McMichael, Mandy Cooper, Hayley D. Germack, Joan Combellick, Krista Koller |
|---|---|
| Rok vydání: | 2022 |
| Předmět: |
Pediatrics
medicine.medical_specialty Health (social science) medicine.medical_treatment Medication Continuation Pregnancy Maternity and Midwifery Humans Medicine Antipsychotic business.industry Mental Disorders Public Health Environmental and Occupational Health Obstetrics and Gynecology medicine.disease Antidepressive Agents Discontinuation Mood Cohort Central Nervous System Stimulants Female Medical Expenditure Panel Survey business Perinatal period Antipsychotic Agents |
| Zdroj: | Women's Health Issues. 32:241-250 |
| ISSN: | 1049-3867 |
| DOI: | 10.1016/j.whi.2021.10.004 |
| Popis: | Background Psychiatric illnesses are common during the perinatal period. The use of antipsychotic medication during pregnancy has increased over the past two decades. In many instances, clinicians agree that untreated psychiatric illness during the perinatal period is more dangerous than the risks imposed by continuing psychotherapeutic medication. We describe patterns of psychotherapeutic medication continuation and discontinuation during pregnancy in a large U.S. cohort. Methods We assessed the relationship between the demographic and clinical characteristics of women who continued or discontinued psychotherapeutic medications—antidepressants, anxiolytics/sedatives, anticonvulsants, antipsychotics, mood stabilizers, and stimulants—during pregnancy. This study used data from 2008 to 2015 from the Medical Expenditure Panel Survey. We used t tests and Medical Expenditure Panel Survey Household Component longitudinal sampling weights in the analysis of this data. Results There were few significant differences noted in clinical and demographic characteristics between women who continued and discontinued medications during pregnancy. Those who continued were less likely to be employed (46.95% of continuers were employed vs. 80.55% of discontinuers; p = .0053). Women taking antipsychotics were more likely to continue medications during pregnancy (64.60% continually used antipsychotics vs. 35.40% discontinued antipsychotics; p = .008), whereas women taking antidepressants were more likely to discontinue their use (19.62% continually used antidepressants vs. 80.38% discontinued antidepressants; p = .032). For each medication category, women resumed medication after pregnancy. Conclusions Antidepressants are the most commonly discontinued psychotherapeutic medication during pregnancy. We recommend further research examining factors that may influence this observed difference. |
| Databáze: | OpenAIRE |
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