Comparison of power Doppler and B-scan sonography for renal imaging using a sonographic contrast agent
| Autor: | Elon Y. Kotlar, Kenneth C. Bovee, James I. Kirchofer, Peter H. Arger, Charles R. Pugh, Chandra M. Sehgal |
|---|---|
| Rok vydání: | 1998 |
| Předmět: |
Pathology
medicine.medical_specialty Image quality media_common.quotation_subject Contrast Media Transit time Kidney Sensitivity and Specificity Power doppler Dogs Image Processing Computer-Assisted medicine Animals Contrast (vision) Radiology Nuclear Medicine and imaging Image analysis media_common Fluorocarbons Radiological and Ultrasound Technology business.industry Ultrasonography Doppler Image Enhancement Renal imaging Regional Blood Flow Renal blood flow business Nuclear medicine Perfusion |
| Zdroj: | Journal of Ultrasound in Medicine. 17:751-756 |
| ISSN: | 0278-4297 |
| DOI: | 10.7863/jum.1998.17.12.751 |
| Popis: | The goal of this study was to evaluate the relative performance of power Doppler and B-scan imaging modes in detecting vascular perfusion changes resulting from injection of a contrast agent. To allow this comparison the imaging plane and the contrast agent injection must be the same for both modes. We achieved this by using a rigid transducer holder and simultaneously recording power Doppler and B-scan images on separate videotapes. The kidneys of five adult beagles were scanned to allow a comparison of how power Doppler and B-scan imaging methods monitor changes during the injection of 0.1 ml/kg of a contrast agent, EchoGen emulsion (Sonus Pharmaceuticals, Bothell, WA). The changes in the images were assessed qualitatively by three radiologists and quantitatively using a custom-designed image analysis software. All of the radiologists agreed that no visually detectable changes occurred in B-scan images but that significant changes could be observed in power Doppler images. Image analysis also indicated a difference between power Doppler and B-scan images. The change in mean color level of power Doppler images could be displayed as an indicator dilution curve with a peak enhancement of 46 +/- 16 above the preinjection value. The time at which mean color level peaked was 18 +/- 13 s. The mean color level returned to half of the peak value by 69 +/- 42 s and returned to the preinjection baseline value by 148 +/- 73 s. Conversely, B-scan images showed statistically insignificant changes, and time measurements could not be made. By all measures used to evaluate images, power Doppler imaging had a greater sensitivity in detecting changes resulting from contrast agent injection than B-scan imaging. This finding indicates that power Doppler imaging of contrast agent injections can be used to map regional differences in flow as well as quantitative measurements of a contrast agent's transit time and has the potential to assess kidney abnormalities associated with renal blood flow. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text