Severe Coagulopathy Secondary to Fulminant Herpes Simplex Virus Hepatitis in a Severely Burned Patient: A Case Report and Review of the Literature
| Autor: | Sonali Patel, Walter L. Ingram, Rachael Williams, Rita Gayed, Gregory Cook, Juvonda Hodge |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Pediatrics
medicine.medical_specialty Hepatitis Viral Human viruses medicine.medical_treatment Fulminant Mucocutaneous zone medicine.disease_cause 03 medical and health sciences 0302 clinical medicine Fulminant hepatic failure Fatal Outcome Coagulopathy Medicine Humans 030212 general & internal medicine Hepatitis business.industry Rehabilitation Immunosuppression Herpes Simplex Blood Coagulation Disorders Liver Failure Acute Middle Aged medicine.disease Herpes simplex virus Emergency Medicine 030211 gastroenterology & hepatology Surgery Female Complication business Burns |
| Zdroj: | Journal of burn careresearch : official publication of the American Burn Association. 39(6) |
| ISSN: | 1559-0488 |
| Popis: | Fulminant hepatic failure secondary to herpes simplex virus (HSV) is a rare complication that is associated with high mortality. Here, we describe the case of a critically ill patient with severe burns and inhalation injury who developed severe coagulopathy during her hospital stay, which was later found to be caused by HSV hepatitis. In addition, we review the current literature on HSV hepatitis. Only three prior reports document liver involvement of HSV in patients with burn. Clinical symptoms, diagnostic factors, and management of HSV hepatitis in patients with burn are presented. Because of severe immunosuppression and potentially fatal nature of this infection, clinicians should have a heightened suspicion for HSV hepatitis in burn patients with HSV mucocutaneous involvement, unexplained liver dysfunction, and severe coagulopathy, and it should prompt immediate initiation of intravenous acyclovir. |
| Databáze: | OpenAIRE |
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