Modulation of lysosomal protease-esterase and lysozyme in Kupffer cells and peritoneal macrophages infected with Nocardia asteroides
| Autor: | Blaine L. Beaman, Elliot Goldstein, M Paliescheskey, R M Donovan, C M Black |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 1986 |
| Předmět: |
Kupffer Cells
medicine.medical_treatment Immunology Acid Phosphatase Nocardia Infections Microbiology Esterase Carboxylesterase chemistry.chemical_compound Peritoneal cavity Mice medicine Animals Peritoneal Cavity Protease biology Macrophages Acid phosphatase Nocardia biology.organism_classification Lysosomal acid phosphatase Infectious Diseases medicine.anatomical_structure chemistry Nocardia asteroides biology.protein Parasitology Muramidase Lysozyme Lysosomes Carboxylic Ester Hydrolases Research Article Peptide Hydrolases |
| Popis: | Virulent Nocardia asteroides reduces lysosomal acid phosphatase activity in murine macrophages. A computer-assisted imaging photometry system was used to quantitate lysozyme and nonspecific esterase-neutral protease levels within individual macrophages following ingestion of nocardiae. In contrast to acid phosphatase, lysozyme and esterase-neutral protease activity was either unchanged or increased following infection by increasing numbers of nocardial cells. |
| Databáze: | OpenAIRE |
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