Lactone Derivatives Produced by a Phaeoacremonium sp., an Endophytic Fungus from Senna spectabilis
| Autor: | Yvonne Primerano Mascarenhas, Amanda Correia Saraiva, Vanderlan da Silva Bolzani, Lucas M. Abreu, Geraldo H. Silva, Henrique C. Trevisan, Helder Lopes Teles, Maria Luiza Zeraik, Ludwig H. Pfenning, Angela Regina Araújo, Camila M. de Oliveira, Alexandra Ivo de Medeiros, Camila P. Nicolli, Maria C. M. Young |
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| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Senna Plant Antifungal Agents Pharmaceutical Science Cladosporium cladosporioides 01 natural sciences Analytical Chemistry Lactones 03 medical and health sciences Acetals Ascomycota Drug Discovery Senna spectabilis Botany Phaeoacremonium Pharmacology chemistry.chemical_classification Molecular Structure biology 010405 organic chemistry Organic Chemistry Ketones Endophytic fungus biology.organism_classification RESISTÊNCIA MICROBIANA ÀS DROGAS 0104 chemical sciences Plant Leaves 030104 developmental biology Complementary and alternative medicine chemistry Phaeoacremonium sp Molecular Medicine Cladosporium Lactone |
| Zdroj: | Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual) Universidade de São Paulo (USP) instacron:USP LOCUS Repositório Institucional da UFV Universidade Federal de Viçosa (UFV) instacron:UFV |
| ISSN: | 1520-6025 0163-3864 |
| DOI: | 10.1021/acs.jnatprod.5b00828 |
| Popis: | Three new isoaigialones, A, B, and C (1–3), along with aigialone (4), were isolated from the crude EtOAc extract of a Phaeoacremonium sp., an endophytic fungus obtained from the leaves of Senna spectabilis. The structures of these compounds were elucidated based on the analysis of spectroscopic data. Compounds 2 and 4 were active against the phytopathogenic fungi Cladosporium cladosporioides and C. sphaerospermum. This is the first report of metabolites produced by an Phaeoacremonium sp., associated with S. spectabilis. |
| Databáze: | OpenAIRE |
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