The Interval Between Initiation of Anti-tuberculosis Treatment in Patients with Culture-positive Pulmonary Tuberculosis and Receipt of Drug-susceptibility Test Results
| Autor: | Sung Koo Han, Young Kil Park, Chang Hoon Lee, Gill Han Bai, Jieun Lee, Young Soo Shim, Jae-Joon Yim, Joon Sung Joh, Eui Chong Kim |
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| Jazyk: | angličtina |
| Rok vydání: | 2007 |
| Předmět: |
Adult
Male medicine.medical_specialty Tuberculosis Time Factors Adolescent Antitubercular Agents Microbial Sensitivity Tests Anti tuberculosis Pulmonary tuberculosis Internal medicine medicine Outpatient clinic Humans In patient Prospective Studies Prospective cohort study Tuberculosis Pulmonary Aged Receipt business.industry General Medicine Drug susceptibility Middle Aged medicine.disease Surgery Treatment Original Article Female business |
| Zdroj: | Journal of Korean Medical Science |
| ISSN: | 1598-6357 1011-8934 |
| Popis: | Although mycobacterial culture and the subsequent drug-susceptibility test (DST) for anti-tuberculosis (TB) drugs take several months to complete using solid media, there are no reports on the turnaround times of these tests under clinical conditions. The aim of this study was to determine the interval between initiation of anti-TB treatment and receipt of DST requested at an outpatient clinic. We prospectively enrolled patients with culture-positive pulmonary TB at Seoul National University Hospital from September 2002 to December 2004. Patients were followed up monthly. Mycobacterial cultures were done using Ogawa media at Seoul National University Hospital. DST were performed at the Korean Institute of Tuberculosis. Of the 104 patients enrolled, 54 were male. The median age was 41 yr. The median interval from initiation of anti-TB treatment to receipt of mycobacterial culture results by clinicians was 37 days (range, 0-89 days). The median interval from initiation of treatment to confirmation of DST by requesting clinicians was 80.5 days (range, 28-145 days). Clinicians only received the results of DST more than two months after initiation of treatment when they followed up patients monthly and mycobacterial culture was performed using solid media. |
| Databáze: | OpenAIRE |
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