Effect of intrauterine t-device and copper-t on in vitro uptake of estradiol-17β-6, 7-3H and progesterone-1, 2-3H in monkey uterus and cervix
| Autor: | Maya Ghosh, S.K. Roy |
|---|---|
| Rok vydání: | 1976 |
| Předmět: |
medicine.medical_specialty
medicine.drug_class Uterus Cervix Uteri Internal medicine Animals Medicine Endocrine system Cervix Progesterone Estradiol business.industry Genitourinary system Obstetrics and Gynecology Haplorhini Macaca mulatta In vitro medicine.anatomical_structure Endocrinology Reproductive Medicine Mechanism of action Estrogen Female medicine.symptom business Copper Intrauterine Devices Hormone |
| Zdroj: | Contraception. 13:355-364 |
| ISSN: | 0010-7824 |
| DOI: | 10.1016/s0010-7824(76)80045-5 |
| Popis: | The uptake of estradiol-17β-6, 7- 3 H and progesterone-1, 2- 3 H in the uterus and cervix was investigated by an in vitro method after intrauterine insertion of the copper-T and plain-T in monkeys. The estrogen uptake in the uterus of the plain-T device inserted monkeys showed an increase as compared to that of the copper-T inserted animals and the intact control group (where the T device was not used). Estrogen uptake in the copper-T and intact control animals did not show any significant difference. The progesterone uptake was increased in intact control monkeys as compared to that of the copper-T and plain-T inserted monkeys. The estrogen and progesterone uptake in the cervix was similar to that observed in the uterus. It appears that the mechanism of action of the copper-T may be different from that of the plain-T. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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