Limitations of current tuberculosis screening tests in immunosuppressed patients

Autor: Vanessa Clifford, Marc Tebruegge, Nigel Curtis
Rok vydání: 2015
Předmět:
Zdroj: BMJ (Clinical research ed.). 350
ISSN: 1756-1833
Popis: We agree that a combination of an interferon γ release assay (IGRA; QuantiFERON-TB Gold in-Tube (QFT-IT) or TSPOT. TB ) and a tuberculin skin test is the most sensitive approach to screening for latent tuberculosis infection in patients with rheumatological diseases before starting biological drugs.1 The authors note that skin tests can be false-negative in patients receiving corticosteroids. However, IGRAs, which are designed primarily to achieve high …
Databáze: OpenAIRE