Quantifying the biochemical state of knee cartilage in response to running using T1rho magnetic resonance imaging
| Autor: | Louis E. DeFrate, Alexie D. Riofrio, Wyatt A. R. Smith, Emily N. Vinson, Charles E. Spritzer, Adam P. Goode, Lauren N. Heckelman, Olivia R. Gwynn, Amber T. Collins, Gangadhar M. Utturkar |
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| Rok vydání: | 2020 |
| Předmět: |
Adult
Cartilage Articular Male medicine.medical_specialty Knee Joint Water flow Quantitative magnetic resonance imaging lcsh:Medicine Asymptomatic Article Running 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Internal medicine medicine Humans lcsh:Science Exercise Multidisciplinary Tibia medicine.diagnostic_test business.industry Cartilage lcsh:R Magnetic resonance imaging Patella 030229 sport sciences Femoral cartilage Magnetic Resonance Imaging Mechanical engineering Knee cartilage medicine.anatomical_structure Cardiology Proteoglycans lcsh:Q medicine.symptom business Biomedical engineering human activities |
| Zdroj: | Scientific Reports, Vol 10, Iss 1, Pp 1-7 (2020) Scientific Reports |
| ISSN: | 2045-2322 |
| DOI: | 10.1038/s41598-020-58573-8 |
| Popis: | Roughly 20% of Americans run annually, yet how this exercise influences knee cartilage health is poorly understood. To address this question, quantitative magnetic resonance imaging (MRI) can be used to infer the biochemical state of cartilage. Specifically, T1rho relaxation times are inversely related to the proteoglycan concentration in cartilage. In this study, T1rho MRI was performed on the dominant knee of eight asymptomatic, male runners before, immediately after, and 24 hours after running 3 and 10 miles. Overall, (mean ± SEM) patellar, tibial, and femoral cartilage T1rho relaxation times significantly decreased immediately after running 3 (65 ± 3 ms to 62 ± 3 ms; p = 0.04) and 10 (69 ± 4 ms to 62 ± 3 ms; p |
| Databáze: | OpenAIRE |
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