Large-scale purification of pachydictyol A from the brown alga Dictyota dichotoma obtained from algal wash and evaluation of its antifouling activity against the freshwater mollusk Limnoperna fortunei
| Autor: | Guillermo Blustein, Mónica García, Miriam Cristina Perez, Gastón E. Siless, Jorge Alejandro Palermo |
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| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
0106 biological sciences
PACHYDICTYOL A Phaeophyceae Dictyota dichotoma LIMNOPERNA FORTUNEI Plant Science Aquatic Science 01 natural sciences PHAEOPHYCEAE Botany Algal wash Limnoperna fortunei Pachydictyol A biology 010405 organic chemistry Antifouling activity 010604 marine biology & hydrobiology Otras Ciencias Químicas Ciencias Químicas Química biology.organism_classification 0104 chemical sciences ALGAL WASH ANTIFOULING ACTIVITY DICTYOTA DICHOTOMA CIENCIAS NATURALES Y EXACTAS |
| Zdroj: | SEDICI (UNLP) Universidad Nacional de La Plata instacron:UNLP |
| DOI: | 10.1007/s10811-017-1261-9 |
| Popis: | A scalable procedure was developed for the extraction and purification of pachydictyol A, the main diterpenoid isolated from the brown alga Dictyota dichotoma. The organic extract of this species is a complex mixture of a large variety of diterpenes, and in this work, the protocol was employed successfully for the purification of gram quantities of this compound from Patagonian D. dichotoma collected from algal wash. Pachydictyol A, together with other minor diterpenoids, was tested for antifouling activity against the invading freshwater mussel Limnoperna fortunei, using a byssal thread formation assay. The results obtained in the study showed a potent antifouling activity for pachydictyol A at 4.7 μg cm−2 disk load. As for the other diterpenoids, dictyoxide was also considerably active, while dictyol C and dictyotadiol had a considerably lower activity. Taking into account the large biomass of algal wash and the abundance of D. dichotoma, together with the effectiveness of the purification protocol, these results show that pachydictyol A and dictyoxide have a good chance to become natural, non-toxic, and ecologically friendly additives in antifouling paints for the protection of submersed structures against L. fortunei. Centro de Investigación y Desarrollo en Tecnología de Pinturas Facultad de Ciencias Naturales y Museo Facultad de Ciencias Agrarias y Forestales |
| Databáze: | OpenAIRE |
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