Heteropolysaccharide-producing bifidobacteria for the development of functional dairy products
| Autor: | Alicia Prieto, María Teresa Dueñas, María Goretti Llamas-Arriba, Eva Rodríguez, Ángela Peirotén, Paloma López, Miguel Angel Pardo, Ana Isabel Puertas |
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| Přispěvatelé: | Eusko Jaurlaritza, Ministerio de Ciencia e Innovación (España), Ministerio de Economía y Competitividad (España), Peirotén, Ángela, Prieto, Alicia, López, Paloma, Dueñas, María Teresa, Peirotén, Ángela [0000-0002-1532-8530 ], Prieto, Alicia [0000-0002-5075-4025], López, Paloma [0000-0001-8755-8952], Dueñas, María Teresa [0000-0001-7551-7037 ] |
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
0106 biological sciences
Bifidobacterium longum Lipopolysaccharide Rhamnose Biology medicine.disease_cause 01 natural sciences law.invention Immunomodulation chemistry.chemical_compound Probiotic 0404 agricultural biotechnology fluids and secretions Bifidobacteria law Exopolysaccharide 010608 biotechnology Technological properties medicine Food science Escherichia coli Zebrafish food and beverages 04 agricultural and veterinary sciences biology.organism_classification 040401 food science Bifidobacterium animalis chemistry Galactose Adhesion bacteria Bacteria Food Science |
| Zdroj: | Repositorio de Resultados de Investigación del INIA INIA: Repositorio de Resultados de Investigación del INIA Digital.CSIC. Repositorio Institucional del CSIC instname Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria INIA |
| Popis: | Bifidobacterium longum INIA P132 and Bifidobacterium infantis INIA P731, isolated from infant-faeces, were investigated in this work. Regarding the probiotic and technological potential of the bifidobacteria, both were resistant to gastrointestinal tract simulated conditions. B. longum showed high survival upon freezing and thawing as well as lyophilisation and was able to grow in milk. B. infantis had higher adhesion capacity to human Caco-2 cells than the commercial probiotic Bifidobacterium animalis BB12 strain. Moreover, both bacteria secrete heteropolysaccharides (HePS) composed of rhamnose, galactose and glucose. In a dextran sodium sulphate-induced enterocolitis model in zebra fish larvae, treatment with each HePS preparation resulted in a decrease of the larval mortality. In addition, the HePS from B. longum immunomodulated in vitro human macrophages treated with the inflammatory Escherichia coli O111:B4 lipopolysaccharide. Thus, both studied bifidobacteria and their HePS have potential beneficial effects on health and thus, to their application in functional foods. This work was supported by a grant from de Department of Environment, Territorial Planification, Agriculture and Fishing and the project no. IT 866-13 from the Basque Government, by the Spanish Ministry of Science and Innovation (AGL 2015-65010-C3-1-R) and by the Spanish Ministry of Economy and Competitiveness (RM12-00004-00-00 and RTA2013-00029-00-00). |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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