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Additional file 1: Supplementary Table 1. Measures of glycemic control. Supplementary Table 2. Number of nondiabetes and diabetes patients on insulin, oral hypoglycemic agents, and diet. Supplementary Table 3. Top ten admission diagnoses in patients admitted for medical or surgical diagnoses. Supplementary Table 4. Odds ratios for the association of hospital mortality on glycemic measures derived from generalised additive model. Supplementary Table 5. Hazard ratios from the Cox proportional hazard model with glucose as time-varying covariate on ICU mortality. Supplementary Table 6. Schoenfeld’s global and individual test for the violation of proportional assumptions of Cox proportional hazard model. Supplementary Figure 1. Patient flow chart. Supplementary Figure 2. Graphical representation of the generalised additive model showing the time weighted average glucose associated with below-average risk of mortality for a) patients with no diabetes and b) patients with diabetes. Supplementary Figure 3. Probability of hospital mortality and time weighted average glucose in medical and surgical patients. Supplementary Figure 4. Probability of hospital mortality and minimum glucose in medical and surgical patients. Supplementary Figure 5. Probability of hospital mortality and coefficient of variation in medical and surgical patients. Supplementary Figure 6. Probability of hospital mortality and time weighted average glucose in trauma and nontrauma patients. Supplementary Figure 7. Probability of hospital mortality and minimum glucose in trauma and nontrauma patients. Supplementary Figure 8. Probability of hospital mortality and coefficient of variation in trauma and nontrauma patients. Supplementary Figure 9. Probability of hospital mortality and time weighted average glucose in diabetes patients on insulin, oral hypoglycemic agents, or diet and patients with no diabetes. Supplementary Figure 10. Probability of hospital mortality and minimum glucose in diabetes patients on insulin, oral hypoglycemic agents, or diet and patients with no diabetes. Supplementary Figure 11. Probability of hospital mortality and coefficient of variation in diabetes patients on insulin, oral hypoglycemic agents, or diet and patients with no diabetes. Supplementary Figure 12. Probability of hospital mortality and time weighted average glucose in all diabetes and nondiabetes patients (including length of stay < 2 days). Supplementary Figure 13. Probability of hospital mortality and minimum glucose in all diabetes and nondiabetes patients (including length of stay < 2 days). Supplementary Figure 14. Probability of hospital mortality and coefficient of variation in all diabetes and nondiabetes patients (including length of stay < 2 days). Supplementary Figure 15. Smoothed scaled Schoenfeld residual plot of glucose on ICU mortality. |
