Epidemiology of Autoimmune Hepatitis (AIH) in the United States Between 2014 and 2019: A Population-based National Study
| Autor: | Gregory S. Cooper, Emad Mansoor, Seth N. Sclair, Mohammed Z. Sheriff, Stanley Martin Cohen, Nahel A. Tunio |
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| Rok vydání: | 2020 |
| Předmět: |
Adult
Male medicine.medical_specialty Prevalence Autoimmune hepatitis White People Article Autoimmune thyroiditis Cohort Studies 03 medical and health sciences 0302 clinical medicine immune system diseases Internal medicine Epidemiology Medicine Humans Child Aged Hepatitis business.industry Gastroenterology Odds ratio medicine.disease digestive system diseases United States Hepatitis Autoimmune 030220 oncology & carcinogenesis Cohort 030211 gastroenterology & hepatology Colitis Ulcerative Female business Cohort study |
| Zdroj: | J Clin Gastroenterol |
| ISSN: | 1539-2031 |
| Popis: | BACKGROUND AND AIMS Autoimmune hepatitis (AIH) is a chronic, inflammatory disease of the liver with increasing prevalence. However, limited epidemiological data exist for the prevalence of AIH in the United States. We used a large database to describe the prevalence of AIH in the United States and the autoimmune diseases associated with it. APPROACH AND RESULTS Data was collected from a commercial database (Explorys Inc., Cleveland, OH), an aggregate of Electronic Health Record data from 26 major integrated health care systems in the United States. We identified a cohort of patients with a diagnosis of AIH from April 2014 to April 2019 based on a Systemized Nomenclature of Medicine-Clinical Terms and calculated the prevalence of AIH. Of the 37,161,280 individuals active in the database from April 2014 to 2019, we identified 11,600 individuals with a diagnosis of AIH with an overall prevalence rate of 31.2/100,000. The prevalence of AIH was increased in females compared with males [odds ratio (OR)=3.21, P |
| Databáze: | OpenAIRE |
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