Good Metabolic Control Is Associated With Better Quality of Life in 2,101 Adolescents With Type 1 Diabetes
| Autor: | Henk-Jan Aanstoot, Patrick Garandeau, Mirjana Kocova, Hannah McGee, Nobuo Matsuura, Oddmund Søvik, Denis Daneman, Hilary Hoey, Jan Åman, Philip Hougaard, Peter G.F. Swift, Pedro Martul, Stephen Greene, Michael Fitzgerald, Reinhard W. Holl, Eugen J. Schoenle, Eero A. Kaprio, Thomas Danne, Rosa Maria Tsou, Helle Lynggaard, Henrik B. Mortensen, Harry Dorchy, Kenneth Robertson, Francesco Chiarelli, Maurizio Vanelli |
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| Rok vydání: | 2001 |
| Předmět: |
Blood Glucose
Cross-Cultural Comparison Male Research design Gerontology medicine.medical_specialty Adolescent Health Status Endocrinology Diabetes and Metabolism Normal Distribution Sex Factors Japan Quality of life Reference Values Surveys and Questionnaires Diabetes mellitus Internal Medicine medicine Humans Child Glycated Hemoglobin Advanced and Specialized Nursing Type 1 diabetes business.industry medicine.disease Cross-cultural studies Surgery Europe Diabetes Mellitus Type 1 Metabolic control analysis North America Cohort Quality of Life Regression Analysis Female business Biomarkers Cohort study |
| Zdroj: | Diabetes Care. 24:1923-1928 |
| ISSN: | 1935-5548 0149-5992 |
| Popis: | OBJECTIVE—It is unclear whether the demands of good metabolic control or the consequences of poor control have a greater influence on quality of life (QOL) for adolescents with diabetes. This study aimed to assess these relations in a large international cohort of adolescents with diabetes and their families.RESEARCH DESIGN AND METHODS—The study involved 2,101 adolescents, aged 10–18 years, from 21 centers in 17 countries in Europe, Japan, and North America. Clinical and demographic data were collected from March through August 1998. HbA1c was analyzed centrally (normal range 4.4–6.3%; mean 5.4%). Adolescent QOL was assessed by a previously developed Diabetes Quality of Life (DQOL) questionnaire for adolescents, measuring the impact of diabetes, worries about diabetes, satisfaction with life, and health perception. Parents and health professionals assessed family burden using newly constructed questionnaires.RESULTS—Mean HbA1c was 8.7% (range 4.8–17.4). Lower HbA1c was associated with lower impact (P < 0.0001), fewer worries (P < 0.05), greater satisfaction (P < 0.0001), and better health perception (P < 0.0001) for adolescents. Girls showed increased worries (P < 0.01), less satisfaction, and poorer health perception (P < 0.01) earlier than boys. Parent and health professional perceptions of burden decreased with age of adolescent (P < 0.0001). Patients from ethnic minorities had poorer scores for impact (P < 0.0001), worries (P < 0.05), and health perception (P < 0.01). There was no correlation between adolescent and parent or between adolescent and professional scores.CONCLUSIONS—In a multiple regression model, lower HbA1c was significantly associated with better adolescent-rated QOL on all four subscales and with lower perceived family burden as assessed by parents and health professionals. |
| Databáze: | OpenAIRE |
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