Thiamine Deficiency Leading to Refractory Lactic Acidosis in a Pediatric Patient
| Autor: | Courtney M. Rowan, Riad Lutfi, Brian D. Leland, Alicia M. Teagarden |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty medicine.medical_treatment Case Report Critical Care and Intensive Care Medicine Gastroenterology 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Refractory Internal medicine medicine Extracorporeal membrane oxygenation 030212 general & internal medicine Renal replacement therapy Intensive care medicine Thiamine deficiency Acidosis 030109 nutrition & dietetics business.industry lcsh:Medical emergencies. Critical care. Intensive care. First aid food and beverages lcsh:RC86-88.9 medicine.disease chemistry Lactic acidosis Etiology Thiamine medicine.symptom business human activities |
| Zdroj: | Case Reports in Critical Care Case Reports in Critical Care, Vol 2017 (2017) |
| ISSN: | 2090-6439 2090-6420 |
| Popis: | Thiamine plays a critical role in energy metabolism. Critically ill children and adults may develop thiamine deficiency with ultimately increased mortality due to potentially irreversible consequences of severe type B lactic acidosis. We report a case of an unvaccinated term neonate with malignant pertussis requiring extracorporeal membrane oxygenation and continuous renal replacement therapy, who developed profound lactic acidosis of unknown etiology. After countless evaluations for likely causes, the patient was ultimately determined to have thiamine deficiency and her acidosis resolved rapidly with vitamin supplementation. |
| Databáze: | OpenAIRE |
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