Atypical Presentation of T-Cell Large Granular Lymphocytic Leukemia Mimicking Pleural Malignancy on 18F-FDG PET/CT
Autor: | Arun Visakh R, Raja Senthil, Thara Pratap, Pushpa Mahadevan, Vadavattathu Padmanabhan Gangadharan |
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Rok vydání: | 2019 |
Předmět: |
Adult
Pathology medicine.medical_specialty Pleural malignancy Lymphocytosis Pleural Neoplasms Large granular lymphocytic leukemia Hepatosplenomegaly Asymptomatic 030218 nuclear medicine & medical imaging Diagnosis Differential 03 medical and health sciences 0302 clinical medicine Fluorodeoxyglucose F18 Positron Emission Tomography Computed Tomography hemic and lymphatic diseases Humans Medicine Cytotoxic T cell Radiology Nuclear Medicine and imaging business.industry General Medicine medicine.disease Leukemia Large Granular Lymphocytic Leukemia 030220 oncology & carcinogenesis Female Lymph medicine.symptom business |
Zdroj: | Clinical Nuclear Medicine. 44:e296-e297 |
ISSN: | 1536-0229 0363-9762 |
DOI: | 10.1097/rlu.0000000000002425 |
Popis: | T-cell large granular lymphocytic leukemia is a rare form of leukemia, caused by clonal proliferation of cytotoxic T-cells, characterized by modest lymphocytosis and cytopenias of other lineage with hepatosplenomegaly and relatively rare lymph nodal involvement. Involvement of other organs is extremely rare. It is predominantly an indolent disease and most of patients remain asymptomatic for a long period. We present a rare case of aggressive form (CD56 positive) of large granular lymphocytic leukemia with atypical presentations mimicking pleural malignancy on F-FDG PET/CT. |
Databáze: | OpenAIRE |
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