The Role of Oviductal Cells in Activating Stallion Spermatozoa
| Autor: | Bart Leemans, Hilde Nelis, Ann Van Soom, Bart M. Gadella, Tom A.E. Stout, Maarten Hoogewijs, Catharina De Schauwer |
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| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
endocrine system medicine.medical_treatment Perivitelline space Biology Andrology 03 medical and health sciences Human fertilization Hyperactivated motility Capacitation In vitro fertilization medicine Acrosome Zona pellucida reproductive and urinary physiology In vitro fertilisation urogenital system Equine Oviduct Sperm Protein tyrosine phosphorylation 030104 developmental biology medicine.anatomical_structure Equid Sperm-oviduct interaction |
| Zdroj: | Journal of Equine Veterinary Science, 43(Supplement), S49. W.B. Saunders Ltd |
| ISSN: | 0737-0806 |
| Popis: | Conventional in vitro fertilization is poorly successful with equine gametes. Although stallion spermatozoa bind to the zona pellucida in vitro, they fail to acrosome react and cannot therefore penetrate into the perivitelline space. Failed sperm penetration most likely relates to the absence in in vitro fertilization media of essential molecules required to fully support stallion sperm capacitation. In vivo, the oviductal lumen provides an environment that appropriately regulates interactions between the gametes and promotes fertilization. Identifying the oviductal “fertilization stimulating factors” would enormously benefit the development of equine in vitro fertilization media. This review focuses on the current understanding of equine sperm–oviduct interactions, which may hold essential clues to achieving successful in vitro fertilization with equine gametes. |
| Databáze: | OpenAIRE |
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