Early visual assessment in preterm infants with and without brain lesions: Correlation with visual and neurodevelopmental outcome at 12 months
| Autor: | Mario G. Romeo, Flaviana Bianco, Domenico M. Romeo, Francesca Perrino, Michela Groppo, Giovanni Baranello, Cilauro S, Costantino Romagnoli, Fabio Mosca, Annalisa Sacco, Alessandra Ometto, Claudia Brogna, Daniela Ricci, Ilaria Contaldo, Luca A. Ramenghi, Silvia Pisoni, Michela Quintiliani, Laura Cesarini, Patrizia Papacci, Francesca Serrao, Francesca Gallini, Eugenio Mercuri, Giovanni Cioni, Frances M. Cowan |
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| Jazyk: | angličtina |
| Rok vydání: | 2011 |
| Předmět: |
Pediatrics
medicine.medical_specialty genetic structures Infant Newborn Visual Acuity Obstetrics and Gynecology Gestational age Brain Lesion Correlation Cohort Studies Child Development Predictive Value of Tests Predictive value of tests Pediatrics Perinatology and Child Health Visual assessment medicine Brain lesions Humans Early childhood medicine.symptom Psychology Infant Premature Vision Ocular Cohort study |
| Popis: | Several studies have reported the development of various aspects of visual function in infancy and early childhood in both preterm and term-born infants, but only a few studies have focused on the predictive power of neonatal visual findings in infants with brain lesions.To explore visual findings at term age, and at 3 and 12 months corrected age in preterm infants (gestational age33 weeks) with and without brain lesions; to compare the assessment at term age and at 12 months; and to assess the relationship between visual findings and neurodevelopmental outcome at 12 months.Cranial ultrasound scans (US) were classified in normal, mild or major abnormalities. One-hundred and forty-five infants were assessed with age specific tests for visual function at term age, and at 3 and 12 months. Neurodevelopmental assessment (Griffiths' Scales) was performed at 12 months.A good correlation was found between early and late visual assessment and neurodevelopment outcome. Of the 121 infants with normal neonatal visual assessment, 119 were also normal at 12 months and 116 had normal developmental quotient. Of the 24 infants with abnormal neonatal visual assessment, 12 were also abnormal at 12 months. All the false positives had normalised by 3 months. Of the 35 infants with major US abnormalities, 20 had normal and 15 abnormal scores on the neonatal assessment. At 1 year 17 had normal and 18 abnormal scores.A normal visual assessment at term age is a good predictor of normal visual and neurodevelopmental outcome at 12 months. An abnormal visual examination in the neonatal period was a less reliable prognostic indicator, infant should be reassessed at 3 months. |
| Databáze: | OpenAIRE |
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