Association among presence of cancer pain, inadequate pain control, and psychotropic drug use
| Autor: | María Paz-Zulueta, Ana Rosa Alconero-Camarero, Miguel Santibáñez, María Cristina Alonso-Blanco, Paloma Salvadores-Fuentes, Paula Parás-Bravo |
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| Přispěvatelé: | Universidad de Cantabria |
| Rok vydání: | 2017 |
| Předmět: |
Male
Cross-sectional study Cancer Treatment lcsh:Medicine Hypnotic 0302 clinical medicine Medicine and Health Sciences Odds Ratio Hypnotics and Sedatives Medicine 030212 general & internal medicine lcsh:Science Analgesics Multidisciplinary Pharmaceutics Medical record Hormonal Therapy Drugs Antidepressants Cancer Pain Middle Aged Antidepressive Agents Psychotropic drug Oncology 030220 oncology & carcinogenesis Anesthesia Antidepressant Female Research Article Antipsychotic Agents medicine.medical_specialty medicine.drug_class 03 medical and health sciences Drug Therapy Adverse Reactions Internal medicine Pain Management Humans Aged Pharmacology Psychotropic Drugs business.industry lcsh:R Odds ratio Confidence interval Cross-Sectional Studies Logistic Models Anti-Anxiety Agents lcsh:Q business Cancer pain Anxiolytics |
| Zdroj: | PLoS ONE 2017 12 (6): e0178742 UCrea Repositorio Abierto de la Universidad de Cantabria Universidad de Cantabria (UC) PLoS ONE PLoS ONE, Vol 12, Iss 6, p e0178742 (2017) |
| Popis: | Introduction Pain is a common symptom in cancer patients, and its control and management are complex. Despite the high concomitant use of psychotropic drugs among such patients, the association among pain, inadequate pain control, and psychotropic drug use has not been fully determined. This study examined the prevalence of cancer pain and inadequate pain control and the association with psychotropic drug use. Materials and methods In this cross-sectional study, we investigated 402 medical records obtained by simple random sampling of oncology patients at a hospital in northern Spain from July 2012 to July 2014. Adjusted odds ratios (ORs) were estimated together with their 95% confidence intervals (95% CIs) by unconditional logistic regression for each type of psychotropic drug (anxiolytics, hypnotics, and antidepressants). Results The mean patient age was 61.17 (standard deviation ± 13.14) years; 57.5% were women, 42.5% men. Pain was present in 18.4% of patients and inadequate pain control in 54.2%. We found a statistically significant association between the presence of cancer pain and anxiolytic use (adjusted OR, 3.15; 95% CI, 1.49–6.68) and hypnotic use (adjusted OR, 5.19; 95% CI, 1.77–15.25). Inadequate pain control was associated to a greater extent with the use of those drugs: adjusted OR for anxiolytic use, 4.74 (95% CI, 1.91–11.80); adjusted OR for hypnotic use, 6.09 (95% CI, 1.74–21.32). By contrast, no association was found between pain and antidepressant use (adjusted OR, 0.99). Conclusion The presence of pain and (to a greater extent) poor pain control were associated with increased use of certain psychotropic drugs, such as anxiolytics and hypnotics. There appeared to be no association between pain and antidepressant use. |
| Databáze: | OpenAIRE |
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