Differential Laboratory Diagnosis of Acute Fever in Guinea: Preparedness for the Threat of Hemorrhagic Fevers
| Autor: | O. A. Stukolova, Alexander E Platonov, Marina V. Safonova, Victoria A Savina, Barré Soropogui, Pavel Semizhon, Vladimir G. Dedkov, N’Faly Magassouba, Jakob Camara |
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| Rok vydání: | 2021 |
| Předmět: |
Health
Toxicology and Mutagenesis 030231 tropical medicine zoonotic pathogens Context (language use) Disease medicine.disease_cause Article Serology Diagnosis Differential 03 medical and health sciences 0302 clinical medicine diagnostics medicine Humans 030212 general & internal medicine Pathogen fever Ebola virus Clinical Laboratory Techniques business.industry acute febrile illness Public Health Environmental and Occupational Health Hemorrhagic Fevers Infectious disease (medical specialty) Immunology Medicine Guinea Differential diagnosis business |
| Zdroj: | International Journal of Environmental Research and Public Health Volume 18 Issue 11 International Journal of Environmental Research and Public Health, Vol 18, Iss 6022, p 6022 (2021) |
| ISSN: | 1660-4601 |
| DOI: | 10.3390/ijerph18116022 |
| Popis: | Acute febrile illnesses occur frequently in Guinea. Acute fever itself is not a unique, hallmark indication (pathognomonic sign) of any one illness or disease. In the infectious disease context, fever’s underlying cause can be a wide range of viral or bacterial pathogens, including the Ebola virus. In this study, molecular and serological methods were used to analyze samples from patients hospitalized with acute febrile illness in various regions of Guinea. This analysis was undertaken with the goal of accomplishing differential diagnosis (determination of causative pathogen) in such cases. As a result, a number of pathogens, both viral and bacterial, were identified in Guinea as causative agents behind acute febrile illness. In approximately 60% of the studied samples, however, a definitive determination could not be made. |
| Databáze: | OpenAIRE |
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