Hormone Receptors and Breast Cancer: Correlations with Clinical and Histologic Features
| Autor: | Maria Cristina Montesco, Carla Arslan Pagnini, Adriano Piffanelli, Pelizzola D, Giovannini G, Alfonso Pluchinotta |
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| Rok vydání: | 1984 |
| Předmět: |
Adult
Oncology Cancer Research Receptor Status medicine.medical_specialty Estrogen receptor Breast Neoplasms 030218 nuclear medicine & medical imaging Lymphocytic Infiltrate Necrosis 03 medical and health sciences 0302 clinical medicine Breast cancer Fibrosis Internal medicine medicine Humans Stage (cooking) Receptor Aged business.industry Age Factors General Medicine Middle Aged medicine.disease Receptors Estrogen Hormone receptor Lymphatic Metastasis 030220 oncology & carcinogenesis Female Receptors Progesterone business |
| Zdroj: | Scopus-Elsevier |
| ISSN: | 2038-2529 0300-8916 |
| DOI: | 10.1177/030089168407000510 |
| Popis: | The possible relationships between hormone receptor status and several clinical (age, gynecologic history, clinical stage) and morphologic aspects (histologic grade, vascular invasion, lymphocytic infiltration, necrosis, fibrosis, elastosis and lymph node metastasis) were evaluated. A highly significant correlation between estrogen receptor levels, patient age, menses regularity and postmenopausal status was found. The histologic features most significantly related to tumor receptor status were histologic grade, lymphocytic infiltrate, necrosis and elastosis. Since these same histologic aspects appear to influence prognosis in breast cancer, the prognostic significance attributed to tumor receptor levels is substantiated. Therefore the importance of this assay is confirmed, not only for its diagnostic and therapeutic purposes, but also for its prognostic value. |
| Databáze: | OpenAIRE |
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