Correlation between pain rating index and end-tidal sevoflurane concentration during sevoflurane anesthesia
| Autor: | Zhe Wang, Wei-Wei Zhang, Jian-Wen Zhang, Zhi-Gan Lv, Baoguo Wang |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Adult
Methyl Ethers Medicine (General) Prospective Clinical Research Report Minimum alveolar concentration Index (economics) Partial Pressure Pain Anesthesia General Biochemistry Pain rating Sevoflurane Correlation 03 medical and health sciences R5-920 0302 clinical medicine 030202 anesthesiology Humans Medicine End tidal sevoflurane concentration Pain rating index business.industry Biochemistry (medical) Cell Biology General Medicine minimum alveolar concentration depth of anesthesia partial pressure of end-tidal carbon dioxide correlation Anesthesia Anesthetics Inhalation business end-tidal sevoflurane concentration 030217 neurology & neurosurgery Sevoflurane anesthesia medicine.drug Processed electroencephalography |
| Zdroj: | The Journal of International Medical Research Journal of International Medical Research, Vol 49 (2021) |
| ISSN: | 1473-2300 0300-0605 |
| DOI: | 10.1177/0300060520987769 |
| Popis: | ObjectiveTo investigate the correlation between the pain rating index (PRi), which is an index derived from processed electroencephalography signals, and the end-tidal sevoflurane concentration (ETsevo).MethodsThis study involved 50 adults with a body mass index of 18 to 25 kg/m2who were undergoing elective surgery under general anesthesia. Thyrocricocentesis was performed with 2.5 mL of 2% tetracaine for endotracheal surface anesthesia, and intravenous injections of midazolam, etomidate, and rocuronium were then administered. The patients’ tracheas were intubated and their ventilatory rate was adjusted to maintain the partial pressure of end-tidal carbon dioxide at 30 to 35 mmHg. Anesthesia was maintained with sevoflurane. The ETsevo was adjusted to maintain anesthesia at 0.6, 0.8, 1.0, and 1.2 minimum alveolar concentration for 15 minutes each, and the PRi, mean arterial pressure (MAP), and heart rate were recorded at each concentration.ResultsA negative correlation was found between the PRi and ETsevo (−0.882) and between the MAP and ETsevo (−0.571). A low positive correlation was found between the PRi and MAP (0.484).ConclusionsThe PRi showed a high negative correlation with the ETsevo. Therefore, the PRi can be used to guide the depth regulation of sevoflurane anesthesia. Clinical trial registration number: ChiCTR-IPR-17012092 |
| Databáze: | OpenAIRE |
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