Membranous nephropathy associated with familial chronic ulcerative colitis in a 12-year-old girl
Autor: | Hans Wolfgang Kreth, Eva Kiss, Nader Gordjani, Hermann J. Gröne, Regina M. Ridder |
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Rok vydání: | 2004 |
Předmět: |
medicine.medical_specialty
Azathioprine Inflammatory bowel disease Gastroenterology Glomerulonephritis Membranous Membranous nephropathy Prednisone Internal medicine Medicine Humans Colitis Child Proteinuria business.industry Glomerulonephritis medicine.disease Ulcerative colitis Nephrology Pediatrics Perinatology and Child Health Colitis Ulcerative Female medicine.symptom business Immunosuppressive Agents medicine.drug |
Zdroj: | Pediatric nephrology (Berlin, Germany). 20(9) |
ISSN: | 0931-041X |
Popis: | Glomerulonephritis is a rare complication in patients with inflammatory bowel disease. We report a case of membranous nephropathy (MN) in a 12.6-year-old girl with chronic ulcerative colitis. The girl was referred to the hospital with bloody diarrhea and arthralgia. Routine urinalysis showed 1 g/m(2) protein excretion in 24 h. Serum ANCA titers were positive. The diagnoses were confirmed by coloscopy and kidney biopsy. The patient's mother had also suffered from ulcerative colitis in adolescence. Proteinuria normalized under treatment with prednisone (60 mg/m(2)/day) and azathioprine, which was initiated to treat the colitis. Chronic ulcerative colitis can be associated with glomerulonephritis. |
Databáze: | OpenAIRE |
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